Patch Test Results in Patients with Allergic Contact Dermatitis in the Western Black Sea Region: A Five-Year Retrospective Study
| Autor: | Koca, Rafet, Altinyazar, Cevdet, Tekin, Nilgun Solak, Cinar, Saniye, Ceylan, Sibel, Sezer, Tuna |
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| Přispěvatelé: | Zonguldak Bülent Ecevit Üniversitesi |
| Jazyk: | turečtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Popis: | WOS: 000298725800008 Background and Design: In this retrospective study, patch test results of 304 patients with allergic contact dermatitis (ACD), who were tested with the European Standard Series, were evaluated. The aim of the study was to determine the frequency of positive reactions to different sensitizers in patients with ACD and to identify sex and age differences. Material and Method: We evaluated a total of 304 patients (195 (64.1%) female and 109 (35.9%) male) who applied to our clinic between the period of January 2003 and December 2008 and who were tested with patch test with the consideration of ACD. Patch test results were assessed according to the International Contact Dermatitis Research Group at 48 and 72 hours after initial application. Results: Lesions of ACD were found to be most frequent on the hands (65.5%). A total of 95 (31.3%) patients had one or more positive patch test reactions. The most common allergens were nickel sulfate (14.8%) followed by cobalt chloride (9.2%), potassium dichromate (6.6%), balsam of Peru (3.6%), fragrance mix (3.3%), mercaptobenzothiazole (3%) and colophonium (2.3%). Positive reactions to nickel sulfate were more common among women, especially those in younger group. Frequency of contact allergy to lanolin, mercapto mix, epoxy resin, paraben mix and quaternium-15 were relatively low, while no positive reaction was obtained to formaldehyde in any case. In 51.6% of patients with positive reaction, the responsible allergen was detected by testing with the European Standard Series. Conclusion: Although this study shows that sensitization rate to metals and fragrance are still high in our region, as well as in our country, and are more frequent in females than in males, future prospective multicenter studies with large number of patients would point out the adequacy of the European Standard Series in our country. (Turkderm 2011; 45: 198-202) |
| Databáze: | OpenAIRE |
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