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Aim: Whether it is possible to differentiate complicated from uncomplicated acute appendicitis (AA) by using complete blood count (CBC) is controversial. In this study, we analysed the predictive value of CBC in differentiating complicated from uncomplicated AA. Methods: In this retrospective study, we analyzed records of patients who underwent appendectomy in our clinic between January 1, 2015 and January 1, 2018. The demographic data and CBC reports were collected. Results: Two hundred thirty-five patients underwent appendectomy due to AA. Of the 235 patients, 164 (69.8%) had non-complicated and 71 (30.2%) had complicated AA. The mean white blood count (WBC), red cell distribution width (RDW), platelet and plateletcrit count were significantly higher in patients with complicated AA than in those with uncomplicated AA (p=0.001; p |