Autor: |
Freeman, T. C., Raza, Sobia, Theocharidis, A., Ghazal, P. |
Jazyk: |
angličtina |
Rok vydání: |
2010 |
Předmět: |
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Zdroj: |
Freeman, T C, Raza, S, Theocharidis, A & Ghazal, P 2010, ' The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways : an intuitive and flexible graphical system for rendering biological pathways ', BMC Systems Biology, vol. 4, no. 65, 65, pp. 1-13 . https://doi.org/10.1186/1752-0509-4-65 |
Popis: |
Background: There is general agreement amongst biologists about the need for good pathway diagrams and a need to formalize the way biological pathways are depicted. However, implementing and agreeing how best to do this is currently the subject of some debate. Results: The modified Edinburgh Pathway Notation (mEPN) scheme is founded on a notation system originally devised a number of years ago and through use has now been refined extensively. This process has been primarily driven by the author's attempts to produce process diagrams for a diverse range of biological pathways, particularly with respect to immune signaling in mammals. Here we provide a specification of the mEPN notation, its symbols, rules for its use and a comparison to the proposed Systems Biology Graphical Notation (SBGN) scheme. Conclusions: We hope this work will contribute to the on-going community effort to develop a standard for depicting pathways and will provide a coherent guide to those planning to construct pathway diagrams of their biological systems of interest. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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