Autor: |
Watson, Mick, Mattock, Jennifer |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Zdroj: |
Watson, M & Mattock, J 2023, ' A comparison of single-coverage and multi-coverage metagenomic binning reveals extensive hidden contamination ', Nature Methods, pp. 1-9 . https://doi.org/10.1038/s41592-023-01934-8 |
DOI: |
10.1038/s41592-023-01934-8 |
Popis: |
Metagenomic binning has revolutionised the study of uncultured microorganisms. This study compares single- and multi-coverage binning on the same set of samples, and demonstrates that multi-coverage binning produces better results than single-coverage binning, and identifies contaminant contigsand chimeric bins that other approaches miss. Whilst resource expensive, multi-coverage binning is a superior approach and should always be performed over single-coverage binning. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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