Zdroj: |
Magliano, D J, Chen, L, Carstensen, B, Gregg, E W, Pavkov, M E, Salim, A, Andes, L J, Balicer, R, Baviera, M, Chan, J C N, Cheng, Y J, Gardiner, H, Gulseth, H L, Gurevicius, R, Ha, K H, Jermendy, G, Kim, D J, Kiss, Z, Leventer-Roberts, M, Lin, C-Y, Luk, A O Y, Ma, S, Mata-Cases, M, Mauricio, D, Nichols, G A, Pildava, S, Porath, A, Read, S, Robitaille, C, Roncaglioni, M C, Lopez-Doriga Ruiz, P, Wang, K-L, Wild, S H, Yekutiel, N & Shaw, J E 2022, ' Trends in all-cause mortality among people with diagnosed diabetes : a multi-country analysis of aggregate data from 21 million deaths in diabetes in high-income settings ', The Lancet Diabetes and Endocrinology, vol. 10, no. 2, pp. 112-119 . https://doi.org/10.1016/S2213-8587(21)00327-2 |
Popis: |
Background Population-level trends in mortality among people with diabetes are inadequately described. Using a multicountry analysis, we aimed to examine the magnitude and trends in excess mortality related to diabetes. Methods We collected data from 1995-2016 on all-cause mortality in people with diagnosed diabetes from 19 data sources in 16 jurisdictions. Data were from administrative sources, health insurance records, registries and a health-survey. Excess mortality was estimated as the standardised mortality ratio (SMR).Findings There were 21 million deaths during 0.5 billion person-years among people with diagnosed diabetes. Seventeen of nineteen data sources showed declines in the age- and sex-standardised mortality rates in people with diabetes, with an annual percentage change in mortality ranging from -4.2% to -0.5%. The largest declines in mortality were observed in East and South East Asia (Hong Kong, South Korea, Taiwan, Singapore). Mortality decreased over time at all ages in most countries, with a suggestion in some countries that the rate of decrease may have been greater at younger ages. Among the 17 data sources with declining mortality among persons with diabetes, we found a significant SMR increase in 5, no significant SMR change in 4, and a significant SMR decrease in 8 jurisdictions.Interpretation and funding All-cause mortality in diabetes has declined in most of the high-income countries we assessed. In nearly 50% of the datasets analysed, mortality decreased more rapidly in people with diabetes than in those without diabetes. Further longevity gains will require continued improvement in prevention and management of diabetes.Funding: This work was funded by the US Centers for Disease Control and Prevention, Diabetes Australia Research Program, and Victoria State Government Operational Infrastructure Support Program. |