Protocol for a systematic review and meta-analysis of experimental models of amyotrophic lateral sclerosis
| Autor: | Gregory, Jenna, Waldron, F. M., Soane, T., Fulton, L., Leighton, D., Chataway, J., Pal, S., Chandran, S., Macleod, M. R. |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Zdroj: | Gregory, J, Waldron, F M, Soane, T, Fulton, L, Leighton, D, Chataway, J, Pal, S, Chandran, S & Macleod, M R 2017, ' Protocol for a systematic review and meta-analysis of experimental models of amyotrophic lateral sclerosis ', Evidence-based Preclinical Medicine, vol. 3, no. 2, pp. 17–19 . https://doi.org/10.1002/ebm2.23 |
| Popis: | Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disease with no cure and limited treatment options. There is therefore an urgent need for effective therapeutic interventions in this disease. This protocol outlines the strategy for a systematic review and meta-analysis to identify, from in vivo animal and human induced pluripotent stem cell (hiPSC) studies, potential therapeutic interventions for ALS. Our aim is to perform a comprehensive review of the ALS literature to compile a list of (1) candidate interventions and (2) target pathways that may be of therapeutic benefit in patients with ALS. |
| Databáze: | OpenAIRE |
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