Pedal Bypass Surgery Prevents Amputation in Patients with Critical Lower Limb Ischemia:A Single Center Experience of 99 Pedal Bypass Operations

Autor: Mejnert Jørgensen, Trine Marie, Michael Jepsen, Jørn, Rai, Amrit, Hallenberg, Christian, Houlind, Kim Christian
Jazyk: angličtina
Rok vydání: 2020
Zdroj: Mejnert Jørgensen, T M, Michael Jepsen, J, Rai, A, Hallenberg, C & Houlind, K C 2020, ' Pedal Bypass Surgery Prevents Amputation in Patients with Critical Lower Limb Ischemia : A Single Center Experience of 99 Pedal Bypass Operations ', Clinics in Surgery, vol. 5, 2915 . < http://www.clinicsinsurgery.com/pdfs_folder/cis-v5-id2915.pdf >
Popis: Background: Bypass surgery below the ankle is now rarely used as prevention of major amputationsdue to critical limb ischemia. We aimed to investigate results after bypass surgery below the ankleperformed at a single center in Denmark. The study was designed as a retrospective, single centrestudy and endpoints were major amputations, overall survival as well as amputation-free andintervention-free survival.Methods: We included all patients undergoing pedal bypass surgery at a single vascular centre inDenmark. Baseline was set as date of surgery and patients were followed until amputation, deathor end of study. The mean amputation-free and overall survival as well as primary and secondarypatency was calculated using Kaplan Meier survival analysis. Cox regression analysis was performedto investigate possible significant co-variables.Results: We included 93 patients with 99 bypasses. 16 patients (16.5%) experienced one or moreopen and/or endovascular bypass revisions and 26 (28%) experienced major amputation. Meanpatency, primary as well as secondary, was 2.6 years. Mean amputation-free survival was 2.9 yearsand mean overall survival 3.9 years.Conclusion: This study shows that in many cases bypass surgery to a pedal artery can preventmajor amputation in patients with critical limb ischemia and that patients undergoing this kind ofsurgery have an expected amputation-free survival comparable to patients undergoing crural bypassoperations above the ankle reported in earlier studies. Therefore, this type of operation should beconsidered as treatment to prevent amputation in patients with no graftable arteries on the lowerleg above the ankle.
Databáze: OpenAIRE