| Autor: |
Woloszynski, T, Podsiadlo, P, Stachowiak, G W, Kurzynski, M, Lohmander, Stefan, Englund, M |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Woloszynski, T, Podsiadlo, P, Stachowiak, G W, Kurzynski, M, Lohmander, S & Englund, M 2012, ' Prediction of progression of radiographic knee osteoarthritis using tibial trabecular bone texture ', Arthritis & Rheumatism, vol. 64, no. 3, pp. 688–695 . https://doi.org/10.1002/art.33410 |
| DOI: |
10.1002/art.33410 |
| Popis: |
OBJECTIVE.: To develop a system for prediction of progression of radiographic knee osteoarthritis (OA) using tibial trabecular bone (TB) texture. METHODS.: We studied 203 knees with (n=68) or without (n=135) radiographic tibiofemoral OA in 105 subjects (90 men, 15 women, mean age 54 years) who had 2 sets of knee radiographs taken 4 years apart. We determined medial and lateral compartment tibial TB texture using an automated region selection method. Three texture parameters were calculated: roughness, degree of anisotropy, and direction of anisotropy based on a signature dissimilarity measure method. We evaluated tibiofemoral OA progression using a radiographic semi-quantitative outcome: an increase in the medial joint space narrowing (JSN) grade. We examined the predictive ability of TB texture in knees with and without pre-existing radiographic OA, with adjustment for age, sex, and body mass index using logistic regression (generalized estimating equations) and receiver operating characteristic curves. RESULTS.: The prediction of increased medial JSN in knees with or without pre-existing radiographic OA was the most accurate for medial TB texture; area under the curve (AUC) was 0.77 and 0.75, respectively. For lateral TB texture, AUC was 0.71 and 0.72, respectively. CONCLUSION.: We have developed a system, based on analyzing tibial TB texture, which yields good prediction of loss of tibiofemoral joint space. The predictive ability of the system needs to be further validated. © 2011 American College of Rheumatology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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