Vitamin D status and PTH in young men: a cross-sectional study on associations with bone mineral density, body composition and glucose metabolism

Autor: Nielsen, Morten Frost, Abrahamsen, B, Nielsen, T L, Hagen, C, Andersen, M, Brixen, K
Jazyk: angličtina
Rok vydání: 2010
Zdroj: Nielsen, M F, Abrahamsen, B, Nielsen, T L, Hagen, C, Andersen, M & Brixen, K 2010, ' Vitamin D status and PTH in young men: a cross-sectional study on associations with bone mineral density, body composition and glucose metabolism ', Clinical Endocrinology, vol. 73, no. 5, pp. 573-80 . https://doi.org/10.1111/j.1365-2265.2010.03847.x
DOI: 10.1111/j.1365-2265.2010.03847.x
Popis: Objective Although vitamin D and bone metabolism are closely related, few studies have addressed the effects of vitamin D status on bone in men at time of peak bone mass. The objectives of this study were to evaluate the prevalence of vitamin D inadequacy in a cross-sectional study in young men and the effects of vitamin D and parathyroid hormone (PTH) on bone mass, bone markers and metabolic function. Design and Participants The study population consisted of 783 men aged 20-29 years. Measurements Bone mineral density (BMD) of the total hip, femoral neck and lumbar spine was measured. dual-energy X-ray absorptiometry was used to evaluate total body fat mass (BFAT). Visceral fat mass and abdominal subcutaneous fat mass (ViFM and ScFM) were assessed using magnetic resonance imaging. A radioimmunoassay was used to measure the level of 25-hydroxy vitamin D (25OHD). Results The prevalence of vitamin deficiency (serum 25OHD
Databáze: OpenAIRE