| Autor: |
Halling, Morten Lee, Nathan, Torben, Kjeldsen, Jens, Jensen, Michael Dam |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Halling, M L, Nathan, T, Kjeldsen, J & Jensen, M D 2014, ' High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn's disease ', Journal of Gastroenterology and Hepatology, vol. 29, no. 5, pp. 992-996 . https://doi.org/10.1111/jgh.12488 |
| Popis: |
Background and Aim: Capsule endoscopy (CE) has a high sensitivity for diagnosing small bowel Crohn's disease, but video analysis is time-consuming. The quick view (qv) function is an effective tool to reduce time consumption. The aim of this study was to determine the rate of missed small bowel ulcerations with qv-CE compared with standard view and the diagnostic accuracy of qv-CE in suspected Crohn's disease. Methods: This study consisted of two parts: (i) 12 small bowel segments with Crohn's disease of varying severity were selected for a detailed analysis of the number and type of lesions visualized with CE and qv-CE, and (ii) a blinded study of the diagnostic accuracy of qv-CE including 40 patients with suspected Crohn's disease. Ileocolonoscopy and CE served as gold standard. Results: Part 1: CE visualized 171 ulcerations compared with 102 detected with qv-CE (miss rate 40%, P=0.02). Part 2: qv-CE identified 15 of 16 patients with small bowel Crohn's disease corresponding to a 94% sensitivity, and overall, 39 out of 40 patients were classified correct (diagnostic accuracy 98%). Qv-CE was false negative in one patient because of a leap of 3min and 20s in the terminal ileum. Reading times varied from 5 to 18min (median 10). Conclusion: Despite a significant number of missed lesions, qv-CE is a safe and time-reducing method for diagnosing small bowel Crohn's disease. To avoid false negative cases, we recommend viewing the terminal ileum in standard view. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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