Acute kidney injury outcomes in covid-19 patients: systematic review and meta-analysis
| Autor: | Silva,Beatriz Moreira, Assis,Letícia Cristina Silva De, Batista Júnior,Maurício De Castro, Gonzalez,Naara Affonso Philipps, Anjos,Samuel Benni Dos, Goes,Miguel Angelo |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Nephrology n.ahead 2022 Jornal Brasileiro de Nefrologia Sociedade Brasileira de Nefrologia (SBN) instacron:SBN |
| Popis: | Background: Acute kidney injury (AKI) is a frequent complication of coronavirus-19 disease (COVID-19). Therefore, we decided to perform a systematic review and meta-analysis with data from the literature to relate the development of COVID-19 associated-AKI with comorbidities, medications, and the impact of mechanical ventilation. Methods: We performed a systematic review using the Newcastle-Ottawa scale and a meta-analysis using the R program. Relevant studies were searched in the PubMed, Medline, and SciELO electronic databases. Search filters were used to include reports after 2020 and cohort studies. Results: In total, 1166 articles were identified and 55 English-written articles were included based on the risk of bias. Of all COVID-19-hospitalized patients presenting with AKI (n = 18029) classified as Kidney Disease Improving Global Outcomes stage 1 to 3, approximately 18% required mechanical ventilation and 39.2 % died. Around 11.3% of the patients required kidney replacement therapy (KRT) and of these, 1093 died and 321 required continuous KRT. Death is more frequent in individuals with AKI [OR 6.03, 95%CI: 5.73-6.74; p |
| Databáze: | OpenAIRE |
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