Determination of selenium toxicity to Oreochromis niloticus based on hematological parameters
| Autor: | Seriani, Robson, Ranzani-Paiva, Maria José Tavares [UNESP], Gonçalves, Adriano [UNESP], Siqueira, Silmara Regina, Lombardi, Julio Vicente |
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| Přispěvatelé: | Instituto de Pesca, Universidade Estadual Paulista (Unesp) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
blood toxicity
leukocyte count selenate animal experiment selenium toxicity hematological parameters cell transformation thrombocytosis animal cell acute toxicity thrombocyte count Selenium toxicity testing neutrophilia Haematological controlled study nonhuman Toxicity animal model Oreochromis niloticus neutrophil monocytosis Water pollution concentration response monocyte erythrocyte leukocyte |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:26:27Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:47:39Z : No. of bitstreams: 1 2-s2.0-84859205266.pdf: 609165 bytes, checksum: 976dbbb5798bd36ab1ad0bc33d8c0860 (MD5) Made available in DSpace on 2014-05-27T11:26:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-04-04 Selenium (Se) is described as an essential micronutrient and participates in different biological functions, as the antioxidant defense systems maintenance and regulation. However, when in high concentrations, Se may cause toxic effects as well as hematological changes in fish. The aim of the present study was to determine the toxicity of selenium in the form of sodium selenate (Na 2Se 6+O 4) in Oreochromis niloticus based on hematological parameters, after exposure to different concentrations (0.01, 0.14 and 1.4 mg Se 6+ L -1). The erythrocytic and leukocytic series were examined over 14 days at intervals of 0, 3, 5, 7,10 and 14 days. The erythrocytic series showed significant alterations in the first 7 days, including the control group. Neutrophils and monocytes showed variations in the first 3 days at a concentration of 1.40 mgSe 6+ L -1 characterizing an acute response. The total number of leukocytes was different in relation to time zero on all Se concentrations. The thrombocyte count also differed statistically from time zero and control in the first 3 days at 0.14 mgSe 6+ L -1. These results indicate that different concentrations induce an acute response with diminution of total leukocytes, neutrophilia, monocytosis and thrombocytosis. Laboratório de Patologia de Organismos Aquáticos Instituto de Pesca, Av. Francisco Matarazzo, 455, 05001-000, São Paulo, São Paulo Centro de Aquicultura Universidade Estadual Paulista Júlio de Mesquita Filho, Jaboticabal, São Paulo Centro de Aquicultura Universidade Estadual Paulista Júlio de Mesquita Filho, Jaboticabal, São Paulo |
| Databáze: | OpenAIRE |
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