Osteoporosis International

Autor: Neves, Frederico Sampaio, Oliveira, L. S. A. F., Torres, Marianna Guanaes Gomes, Toralles, Maria Betânia Pereira, Silva, M. C. B. O. da, Campos, M. I. G., Campos, Paulo Sérgio Flores, Rebello, Iêda Margarida Crusoé Rocha
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
DOI: 10.1007/s00198-011-1810-z
Popis: Texto completo: acesso restrito. p. 2037-2042 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-04T13:47:28Z No. of bitstreams: 1 M. C. B. O. da Silva.pdf: 269385 bytes, checksum: 0d1f2abfb88e059797b599e7d1f948a0 (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-29T15:49:59Z (GMT) No. of bitstreams: 1 M. C. B. O. da Silva.pdf: 269385 bytes, checksum: 0d1f2abfb88e059797b599e7d1f948a0 (MD5) Made available in DSpace on 2014-09-29T15:49:59Z (GMT). No. of bitstreams: 1 M. C. B. O. da Silva.pdf: 269385 bytes, checksum: 0d1f2abfb88e059797b599e7d1f948a0 (MD5) Previous issue date: 2012-07 Summary In sickle cell disease, erythroid hyperplasia causes trabecular destruction leading to low bone density. This condition could be suspected by the radiomorphometric indices and your diagnosis becomes relevant in a multidisciplinary context of health care for sickle cell subjects, providing prognostics and contributing to determine adequate therapeutic and preventive actions. Introduction The aim of this study was to assess the risk of low bone density in subjects with sickle cell disease (SCD) through analysis of panoramic radiographic exams by radiomorphometric indices. Methods Seventy-eight Brazilian subjects with SCD took part in this study and were subdivided into four groups: (I) 31 SCD subjects aged under 40 years; (II) 13 SCD subjects aged 40 years or more; (III) 12 normal subjects aged under 40 years; and (IV) 22 normal subjects aged 40 years or more. In the panoramic radiographs, the mandibular cortical index (MCI) classification, increased spacing of the trabecular bone, panoramic mandibular index (PMI), and mental index (MI) were evaluated. Exact Fisher's test was used to compare age between the different groups. Descriptive analysis of the data was performed to evaluate the simple visual estimation of low bone density (increased bone trabecular space and MCI), and a one-way analysis of variance (Bonferroni criteria) was used to compare the means of the quantitative indices (PMI and MI). The significance level was p
Databáze: OpenAIRE