An?lise do efeito da terapia por fotobiomodula??o (LED 630 nm; 300mw; 9 j/cm2) sobre a tendinite aguda experimental

Autor: Evangelista, Andr? Nobre
Přispěvatelé: Oliveira, Murilo Xavier, Machado, Alex Sander Dias, Machado, Tha?s Peixoto Gaiad, Souza, Renato Aparecido de, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
Jazyk: portugalština
Rok vydání: 2019
Předmět:
Zdroj: Repositório Institucional da UFVJM
Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
instacron:UFVJM
Popis: O presente trabalho foi realizado com apoio da Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - Brasil (CAPES) - C?digo de Financiamento 001. Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2019-12-19T18:22:13Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) andre_nobre_evangelista.pdf: 1444000 bytes, checksum: 076d80520cb2393f155e5be68f2a4d1f (MD5) Approved for entry into archive by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2019-12-19T18:23:03Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) andre_nobre_evangelista.pdf: 1444000 bytes, checksum: 076d80520cb2393f155e5be68f2a4d1f (MD5) Made available in DSpace on 2019-12-19T18:23:03Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) andre_nobre_evangelista.pdf: 1444000 bytes, checksum: 076d80520cb2393f155e5be68f2a4d1f (MD5) Previous issue date: 2019 Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) S?o poucos os estudos que fundamentam a utiliza??o da fotobiomodula??o (FBM) no tratamento da tendinite e os par?metros de aplica??o ainda permanecem controversos. O objetivo deste estudo foi investigar os efeitos da terapia LED de baixa intensidade(630nm) sobre a tendinite aguda induzida no tend?o calc?neo em ratos Wistar. Foram utilizados 30 animais com aproximadamente doze semanas de vida, selecionados aleatoriamente e distribu?dos em 3 grupos: grupo CONTROLE (n=8), grupo TENDINITE (n=11), grupo LED (n=11). A tendinite foi induzida nos grupos TENDINITE e LED por meio de inje??o peritend?nea de 100?L de colagenase. Os animais do grupo LED foram irradiados 1 hora ap?s a les?o (630nm ? 20 nm; DE: 9 J/cm2; tempo de 30s) e estas aplica??es foram repetidas a cada 24 horas em um per?odo de 7 dias. Os animais foram eutanasiados 24 horas ap?s o t?rmino das aplica??es. Ap?s os procedimentos de eutan?sia os tend?es do calc?neo do lado direito foram removidas e realizadas as an?lises qualitativas histol?gicas, histoqu?mica e imunohistoqu?mica. Houve aumento no n?mero de ten?citos, da angiog?nese, aparecimento do tecido de granula??o e uma express?o maior da prote?na Hsp70 no grupo tratado com o LED do que nos grupos controle e tendinite. Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2019. There are few studies that support the use of Photobiomodulation (PBM) in the treatment of tendonitis and the application parameters still remain controversial. The objective of this study was to investigate the effects of low intensity LED therapy (630nm) on acute tendinitis induced in the calcaneus tendon in Wistar rats. We used 30 animals ? 12 weeks of life randomly selected and distributed in 3 groups: CONTROL group (n = 8), TENDINITE group (n = 11), LED group (n = 11). Tendonitis was induced in the tendinitis and led groups by means of peritendinous injection of 100 ?L of collagenase. The animals in the LED group were irradiated 1hour postinjury (630 ? 20 nm; DE: 9 J/cm2, time of 30 s) and these applications were repeated every 24 hours over a period of 7 days. The animals were euthanized 24 hours after the end of the applications. After the euthanasia procedures the right calcaneus tendons were removed and histological, histochemical and immunohistochemical were performed. There was an increase in the number of tenocytes, of the angiogenesis, appearance of the granulation tissue and a greater expression of the Hsp70 protein in the Led group than in the control and tendinitis groups.
Databáze: OpenAIRE
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