Brazilian Journal of Medical and Biological Research

Autor: Ventura, R. R., Olivares, E. L., Passos Junior, D. B., Ramalho, Maria José Pedreira, Rodrigues, José Antunes, Reis, L. C.
Jazyk: angličtina
Rok vydání: 2001
Předmět:
Zdroj: Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
DOI: 10.1590/S0100-879X2001000300016
Popis: p. 407-411 Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2012-10-24T19:15:25Z No. of bitstreams: 1 Ventura, R.R..pdf: 161629 bytes, checksum: 1cba628d580609dd05b82229b895b55b (MD5) Made available in DSpace on 2012-10-24T19:15:25Z (GMT). No. of bitstreams: 1 Ventura, R.R..pdf: 161629 bytes, checksum: 1cba628d580609dd05b82229b895b55b (MD5) Previous issue date: 2001 Rats rendered hypothyroid by treatment with methimazole develop an exaggerated sodium appetite. We investigated here the capacity of hypothyroid rats (N = 12 for each group) to respond to a low dose of captopril added to the ration, a paradigm which induces an increase in angiotensin II synthesis in cerebral areas that regulate sodium appetite by increasing the availability of circulating angiotensin I. In addition, we determined the influence of aldosterone in hypothyroid rats during the expression of spontaneous sodium appetite and after captopril treatment. Captopril significantly increased (P
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