Oral Lichen Planus: Clinical Profile and Determination of Oral Epithelial Dysplasia
| Autor: | Paiva,Seani Neumann, Braga,Cláudia Cristina, Almeida-Coburn,Karla Loureiro, Bautz,Willian Grassi, de Barros,Liliana Aparecida Pimenta, da Gama-de-Souza,Letícia Nogueira |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | International journal of odontostomatology v.10 n.1 2016 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Oral lichen planus (OLP) is the most common noninfectious oral disease and is considered a potentially malignant disorders (OPMDs). The etiology and pathogenesis of OLP are not completely understood and the malignant transformation remains under discussion. The aim was to asses the cytological and histological features of OLP, and establish relationship between clinical and microscopic profiles. A total of 10 patients diagnosed with OLP were investigated. Slides were prepared and stained with HematoxylinEosin to identify 8 histological features and 8 cytological alterations. Finally, oral epithelial dysplasia degree was determined. Hyperplasia and loss of polarity of basal cells were detected in 90 % of cases. Anisonucleosis, nuclear pleomorphism and hyperchromasia affected 100 % of the sample. Six cases were classified as mild-grade OED, with no cases of severe-grade. Microscopic alterations were higher in women (P |
| Databáze: | OpenAIRE |
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