Citral reduces nociceptive and inflammatory response in rodents

Autor: Quintans-Júnior, Lucindo José, Guimarães, Adriana Gibara, Santana, Marília Trindade de, Araújo, Bruno Eduardo Silva de, Moreira, Flávia Viana, Bonjardim, Leonardo Rigoldi, Araújo, Adriano Antunes de Souza, Quintans, Jullyana de Souza Siqueira, Antoniolli, Ângelo Roberto, Soares, Marco Antonio Botelho, Almeida, Jackson Roberto Guedes da Silva, Santos, Márcio Roberto Viana dos
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Repositório Institucional da UFS
Universidade Federal de Sergipe (UFS)
instacron:UFS
Popis: Citral (CIT), which contains the chiral enantiomers, neral (cis) and geranial (trans), is the majority monoterpene from Lippia alba and Cymbopogon citratus. The present study aimed to evaluate CIT for antinociceptive and anti-inflammatory activities in rodents. Antinociceptive and anti-inflammatory effects were studied by measuring nociception through acetic acid and formalin tests, while inflammation was verified by inducing peritonitis and paw edema with carrageenan. All tested doses of CIT had significant protection (p
Databáze: OpenAIRE