Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature

Autor: Trentadue,Mirko, Sozzi,Carlo, Idolazzi,Luca, Lazzarini,Gianluigi, Murano,Riccardo Sante, Gatti,Davide, Rossini,Maurizio, Piovan,Enrico
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Radiologia Brasileira v.55 n.4 2022
Radiologia Brasileira
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
Popis: Objective: To promote advanced research using magnetic resonance imaging (MRI) in the diagnosis of and screening for osteoporosis by looking for correlations among the T-scores measured by dual-energy X-ray absorptiometry (DEXA), the apparent diffusion coefficient (ADC) values on diffusion-weighted imaging (DWI), and the T1-weighted signal intensity values. Materials and Methods: This was a prospective study of postmenopausal women with no contraindications to MRI and no history of cancer who underwent DEXA within 30 days before or after the MRI examination. A 3.0-T scanner was used in order to acquire sagittal sequences targeting the lumbar spine. Results: Thirteen women underwent DEXA and MRI. In two cases, the MRI was discontinued early. Therefore, the final sample comprised 11 patients. The ADC values and T1-weighted signal intensity were found to be higher in patients with osteoporosis. However, among the patients > 60 years of age with osteoporosis, ADC values were lower and T1-weighted signal intensity was even higher. Conclusion: It is unlikely that MRI will soon replace DEXA for the diagnostic workup of osteoporosis. Although DWI and ADC mapping are useful for understanding the pathophysiology of osteoporosis, we believe that T1-weighted sequences are more sensitive than is DWI as a means of performing a qualitative analysis of vertebral alterations.
Databáze: OpenAIRE