Leptin, ghrelin and adiponectin in isctsting adolescent mothers and its relationship with maternal and infant body composition

Autor: Rezende, Elaine Pereira de
Přispěvatelé: Bezerra, Flávia Fioruci, Koury, Josely Correa, Azeredo, Vilma Blondet de
Jazyk: portugalština
Rok vydání: 2012
Předmět:
Zdroj: Biblioteca Digital de Teses e Dissertações da UERJ
Universidade do Estado do Rio de Janeiro (UERJ)
instacron:UERJ
Popis: Submitted by Boris Flegr (boris@uerj.br) on 2021-01-05T16:43:38Z No. of bitstreams: 1 Dissert_Elaine Pereira de Rezende.pdf: 1304561 bytes, checksum: e3da3ce57e1e21cd16797d78b2f56196 (MD5) Made available in DSpace on 2021-01-05T16:43:38Z (GMT). No. of bitstreams: 1 Dissert_Elaine Pereira de Rezende.pdf: 1304561 bytes, checksum: e3da3ce57e1e21cd16797d78b2f56196 (MD5) Previous issue date: 2012-05-03 The hormones ghrelin, leptin and adiponectin are related to body weight control and to energy metabolism, and may also be involved with maternal body composition changes during lactation. Ghrelin, leptin and adiponectin are present in human milk and may also play a role in the infant energy metabolism in the first months of life. The aim of this study was to determine blood concentrations of leptin, ghrelin and adiponectin in lactating adolescents and investigate its correlation with milk concentrations of these hormones and with body composition of the mother and their infants. Fifty five lactating adolescents (14 - 19 years old) were enrolled at the Maternidade Escola UFRJ health care. Maternal Blood and maternal milk samples were collected after overnight fasting. Anthropometric evaluation and body composition assessment using Dual-Energy X-Ray absorptiometry (DXA) were performed in the lactating mother and their infants (10-58 days postpartum). Blood and milk concentrations of ghrelin, leptin and adiponectin were analyzed by enzymatic immunoassay (ELISA). Kolmogorov-Smirnov test was used to verify the normality distribution of data, which were presented as mean ± standard deviation. Associations between variables were evaluated using Pearson s correlation analysis. Additionally, associations involving infant body composition were also investigated after adjustments for postpartum period by partial correlation analysis. Concentrations of leptin, ghrelin and adiponectin in milk (0,51±0,4 ng/mL,106±80 pg/mL, 0,11±0,69 µg/mL respectively) were lower (p
Databáze: OpenAIRE
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