Contraception
| Autor: | Coutinho, Elsimar Metzker, Spinola, Paulo, Barbosa, Ione Cristina, Gatto, Marisa, Tomaz, Geraldez, Morais, Kleber, Yazlle, Marta Edna |
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| Jazyk: | angličtina |
| Rok vydání: | 1997 |
| Předmět: | |
| Zdroj: | Repositório Institucional da UFBA Universidade Federal da Bahia (UFBA) instacron:UFBA |
| DOI: | 10.1016/S0010-7824(97)00018-8 |
| Popis: | Texto completo: acesso restrito. p.175–181 Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2013-02-04T14:06:18Z No. of bitstreams: 1 Coutinho.pdf: 753184 bytes, checksum: aac94c09e3589e85942b707d174bc18c (MD5) Approved for entry into archive by Fatima Cleômenis Botelho Maria (botelho@ufba.br) on 2013-02-04T14:17:38Z (GMT) No. of bitstreams: 1 Coutinho.pdf: 753184 bytes, checksum: aac94c09e3589e85942b707d174bc18c (MD5) Made available in DSpace on 2013-02-04T14:17:38Z (GMT). No. of bitstreams: 1 Coutinho.pdf: 753184 bytes, checksum: aac94c09e3589e85942b707d174bc18c (MD5) Previous issue date: 1997 Healthy, regularly menstruating women, aged 14–38 years, were enrolled in a comparative, double-blind, phase III, clinical trial to evaluate the contraceptive efficacy and acceptability of a combination of 90 mg dihydroxyprogesterone acetophenide with 6 mg estradiol enanthate compared to the commercially available contraceptive combination of 150 mg dihydroxyprogesterone acetophenide with 10 mg estradiol enanthate. Subjects received the contraceptive combination intramuscularly, between the 7th and 10th day of each menstrual cycle, during 12 consecutive menstrual cycles. Approximately 60% of the subjects in both groups completed the study. Principal reasons for discontinuation were personal, nonmedical reasons. Principal medical reasons for discontinuation were menstrual-related, irregular bleeding being the most frequent. Differences in menstrual patterns between the two groups did not lead to differences in discontinuation rates. Three contraceptive failures occurred during the trial, one in Group A (View the MathML source) and two in Group B (View the MathML source), indicating that the lower dose formulation is at least as efficient as the higher dose. |
| Databáze: | OpenAIRE |
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