Non-ionizing radiation effect on the markup of blood cells with 99 mtc in vitro
| Autor: | Martiniano, Carlos Ricardo de Queiroz, Marques, Lídia Audrey Rocha Valadas, Rodrigues Neto, Edilson Martins, Lotif, Mara Assef Leitão, Diógenes, Érika Sabóia Guerra, Capistrano, Allana Bezerra, Thé, Mayra Furtado Dias Filgueira, Silva, Francisco Filipe Carvalho da, Catanho, Maria Teresa Jansem de Almeida |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Repositório Institucional da Universidade Federal do Ceará (UFC) Universidade Federal do Ceará (UFC) instacron:UFC |
| Popis: | The energy density of low power, laser and electromagnetic field , has been used in recent years quite often in the medical field . The study of labeling red blood cells with technetium 99m is used for various evaluations in nuclear medicine including the study of blood volume in neurological intensive care . The aim was to evaluate the in fluence of non - ionizing radiation on the red blood cells labeled in vitro . B lood samples from rats of the Wistar strain divided into two groups were used. The first group used the EDTA and heparin as anticoagulants and received low - power laser induction ( L PL) in the following separately energy density : 3, 6, 9 and 18J/cm². The second group received an electromagnetic field (EMF ) of 60 Hz for 2, 4 , 17 and 21 hours separately . After the induction of the laser and the electromagnetic field , the blood samples w ere labeled with technetium - 99m ( 99mTc). The results indicate that the presence of anticoagulants is able to modify the uptake of technetium - 99m by red blood cells . The laser induced decreases the binding capacity of the technetium - 99m from 3J/cm². From th e foregoing it was found that the radiation is non - ionizing EMF with LBP or alters the binding capacity of 99mTc the erythrocytes and the use of heparin as an anticoagulant gave also a higher labeling efficiency compared with the use of EDTA.The non - ionizi ng radiation has a promising power applications of biomedical sciences can be used for marking targets macromolecules in the body in order to diagnostic procedures and disease control. |
| Databáze: | OpenAIRE |
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