Intake of sucrose solution and paradoxical sleep deprivation in the rat
| Autor: | Pezzato, Fernanda Augustini [UNESP], De Paula, Hugo Garrido Medeiros [UNESP], Bosqueiro, José Roberto [UNESP], Hoshino, Katsumasa [UNESP] |
|---|---|
| Přispěvatelé: | Universidade Estadual Paulista (UNESP) |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Made available in DSpace on 2022-04-29T07:13:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 Background: Paradoxical sleep deprivation (PSD) is known for its antidepressive property, both in humans and experimental animals. The small platform method used to promote PSD in rats, however, involves stress similar to that observed in the methods used to induce depressive-like state. Objective and methods: As sucrose solution intake is validated as a depressive-state marker in the rat, the present study evaluated such parameter before, during and after PSD carried out by the small platform method. Results: The daily mean sucrose solution (15%) ingested by a group of 11 adult male Wistar rats was progressively reduced with PSD. The daily fall in sucrose intake was statistically significant (t-test, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|