Self-propelled particle model for cell-sorting phenomena

Autor: Belmonte, Julio Monti, Thomas, Gilberto Lima, Brunnet, Leonardo Gregory, Almeida, Rita Maria Cunha de, Chate, Hugues
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Popis: A self-propelled particle model is introduced to study cell sorting occurring in some living organisms. This allows us to evaluate the influence of intrinsic cell motility separately from differential adhesion with fluctuations, a mechanism previously shown to be sufficient to explain a variety of cell rearrangement processes. We find that the tendency of cells to actively follow their neighbors greatly reduces segregation time scales. A finite-size analysis of the sorting process reveals clear algebraic growth laws as in physical phase-ordering processes, albeit with unusual scaling exponents.
Databáze: OpenAIRE