Cohort study on canine emigration and leishmania infection in an endemic area for american visceral leishmaniasis. Implications for the disease control

Autor: Silva, M. Paranhos, Nascimento, E. G., Melro, M. C. B. F., Oliveira, G. G. S., Santos, Washington Luis Conrado dos, Carvalho, Lain Carlos Pontes de, Santos, A. J. Oliveira dos
Jazyk: angličtina
Rok vydání: 1998
Předmět:
Zdroj: Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
DOI: 10.1016/S0001-706X(97)00116-2
Popis: Texto completo: acesso restrito. p.75–83 Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2013-01-30T15:17:23Z No. of bitstreams: 1 Silva.pdf: 283577 bytes, checksum: 8eb65fd7af1df62137a923390c4b7ceb (MD5) Made available in DSpace on 2013-01-30T15:17:23Z (GMT). No. of bitstreams: 1 Silva.pdf: 283577 bytes, checksum: 8eb65fd7af1df62137a923390c4b7ceb (MD5) Previous issue date: 1998 American visceral leishmaniasis is a main public health matter in Brazil. Since dogs have been incriminated as the main urban reservoir of AVL agent Leishmania chagasi, a cohort study aimed at understanding the dynamics of the canine infection was carried out in Jequié—an endemic community in the Northeast of Brazil. The inhabited urban and periurban areas of Jequié were divided into 140 clusters of 0.25 km2. All 1681 dogs domiciled in 34 randomly selected clusters were screened for Leishmania antibodies in an enzyme-linked immunosorbent assay. After the seropositive dogs were painlessly eliminated, a cohort of 1286 seronegative dogs was followed up for 18 months, yielding a total of 1739.7 dog-years. The overall incidence of Leishmania infection, as assessed by the detection of Leishmania antibodies in blood samples collected every six months, was 6.55 cases/100 dog-years (95% confidence interval; CI 6.04–7.26). Two subsets of clusters, with 0.70 and 1.35 relative risks of infection, were identified. The annual emigration rate was 2.26 cases/100 dog-years (95% CI 1.86–2.66). The implications of these findings for the control of American visceral leishmaniasis are discussed.
Databáze: OpenAIRE
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