The Brazilian Journal of Infectious Diseases

Autor: Nóbrega, Isabella Pereira da, Silva, Paula Dantas Meireles, Rocha, Priscila, Rios, Isabela, Abrahao, Marcos Herculano Nunes, Netto, Eduardo Martins, Alves, Carlos Roberto Brites
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Repositório Institucional da UFBA
Universidade Federal da Bahia (UFBA)
instacron:UFBA
DOI: 10.1016/j.bjid.2012.10.018
Popis: Texto completo. Acesso restrito. p. 184–193 Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-06-25T18:49:59Z No. of bitstreams: 1 222222222222222.pdf: 317863 bytes, checksum: 7c37026d05d4513246451821326d588b (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-10-31T17:49:32Z (GMT) No. of bitstreams: 1 222222222222222.pdf: 317863 bytes, checksum: 7c37026d05d4513246451821326d588b (MD5) Made available in DSpace on 2013-10-31T17:49:32Z (GMT). No. of bitstreams: 1 222222222222222.pdf: 317863 bytes, checksum: 7c37026d05d4513246451821326d588b (MD5) Previous issue date: 2013 Background: The occurrence of syphilis and HIV-1 infections during pregnancy are major risks to the fetus due to mother-to-child transmission (MTCT). Objectives: To determine peripartum seroprevalence and risk factors of syphilis and HIV-1 infection among pregnant women in Salvador, Brazil, and the rate of HIV-1 MTCT. Methods: Cross-sectional study of pregnant women who were admitted for delivery in a reference maternity hospital between May 2008 and March 2009 was conducted. Women were screened for HIV-1 infection and syphilis, and interviewed regarding demographic, behavioral and obstetric data. Newborns to HIV-infected mothers were tested by b-DNA and DNA-PCR to detect HIV-1. Results: A total 3300/8516 women were evaluated. Mean age was 25.8 ± 7.3 years. HIV-1 and syphilis seroprevalence rates were 0.84% (28/3300) and 0.51% (17/3300), respectively. HIV- 1 infection was associated with: low education (p = 0.04), having a partner with known HIV infection (p < 0.0001) or with previous sexually transmitted infection (p < 0.0001), blood transfusion (p = 0.003), or accidental exposure to blood (p = 0.003). Syphilis was associated with being Caucasian (p = 0.02), having no steady partner (p = 0.02), being a housewife (p = 0.01), having an intravenous drug user (IVDU) sexual partner (p = 0.04) or a sexual partner with previous STI (p < 0.001). Higher education (p = 0.04) was protective against HIV-infection. Attending a prenatal care program was protective against syphilis (p = 0.008) and HIV-1 (p = 0.02). No case of HIV-1 MTCT was detected, but 25% of children born to HIV-infected mothers were lost to follow up. Conclusions: In Salvador, peripartum prevalence of syphilis and HIV-1 infection among pregnant women were low, and associated with classic risk factors for both infections. The great proportion of very late diagnosis of HIV infection, and the high rate of loss of follow-up among positive mothers and their infants are of high concern. Salvador
Databáze: OpenAIRE
Externí odkaz: