Hierro intravenoso en la terapia del síndrome de piernas inquietas

Autor: MIRANDA C.,MARCELO, BUSTAMANTE C.,M. LEONOR
Jazyk: Spanish; Castilian
Rok vydání: 2019
Předmět:
Zdroj: Revista médica de Chile v.147 n.12 2019
SciELO Chile
CONICYT Chile
instacron:CONICYT
Popis: Restless legs syndrome (RLS) may severely affect the quality of life of patients. A deficient iron incorporation into the central nervous system has an important role in the pathophysiology of RLS. Severely affected patients may not respond to current therapeutic options. We report a preliminary experience with five patients with severe RLS and low serum ferritin levels who did not improve with oral iron. All were treated with 1 g of intravenous iron carboxymaltose. They experienced a marked improvement in symptoms, evident even during the first week of therapy that had persistent after up to two years of follow-up. A significant change in the RLS severity scale was observed after intravenous iron. Serum ferritin levels increased in all of them. Intravenous iron could be a therapeutic option for patients with severe RLS.
Databáze: OpenAIRE