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Aim: Analyze dangerous drug interactions and interactions with others substances in ambulatory care practice and reveal the pharmacist role in order to avoid them. Tasks: 1. Choose dangerous drug interactions from analyzed scientific literature in pursuance to reveal pharmacist role in avoiding them. 2. Estimate practical role of pharmacist with on the basis of analyzed anonymous questionnaire. Objectives and methods: The participants of the research project – pharmacists working in community pharmacies, patients taking statins and patients taking ACE inhibitors. Test method – an anonymous questionnaire. In total there were 230 questionnaires distributed to pharmacists, 179 questionnaires were returned fully completed (response rate 77,80proc.). In total there were distributed 550 questionnaires to patients, 406 questionnaires were returned fully completed (response rate 73,50 proc.). The statistical analysis was performed using SPSS (Statistical Package for Social Science) 17.0 Results: 39 % of respondents are taking ACE inhibitors with potassium supplements. 14 % of respondents are taking statins with grapefruits. About possible drug interaction know about 50 % of patients who are taking ACE inhibitors or statins. 89 % of pharmacists claim that they inform patients about drug interaction, but according to patients – 21-34 % of them know about interactions from pharmacists. Those pharmacists who work in cities or those who work longer than 21 years know and inform less about drug interactions than those, who work in cities or work less than 5 years. Pharmacists who read SPC know about drug interaction 2,4 times more. Patient knowledge about drug interaction increase about 25 % when pharmacists inquire patient what drug they are taking. Conclusion:1.According to drug consumption and literature common drug interactions are ACE inhibitors with potassium supplements and statins with grapefruit or grapefruit juice components. 2. Pacients knowledge about drug interactions is not sufficient – about 50 proc. of patient who are taking ACE inhibitors or statins knows about drug interaction. Too much of patients (39 %) are taking ACE inhibitors with potassium supplements. 3. Pharmacists role is not sufficient despite that they can significantly take part in avoiding drug interaction: pharmacists inquire half of patients if they are taking additiniol drugs or supplements. Almost half of the patients who are taking ACE inhibitors consume potassium supplements. Consumption of this combination increase with age. 4. SPC reading and patients inquiring about additional drug or supplement consumption improve pharmacist role in avoiding drug interactions. |
