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“Radiologic diagnostic possibilities of non-invasive breast cancer detection” by R. Ereminas. The aim is to rate optimal radiological research method for non-invasive breast cancer detection. Research tasks: 1. To identify the most common features for non-invasive breast cancer in mammographic (MG), ultrasound (US) and magnetic resonance imaging (MRI) tests. 2. To evaluate the correlation of radiological changes with clinical and histological data. 3. To compare accuracy of different radiological tests. Research methods: a retrospective study. 43 women, who were diagnosed with non-invasive breast cancer and were treated in LUHS KK Breast Surgery departament (2013-2015), case histories were analyzed. Evaluating the clinical data, non-invasive cancer onset of symptoms in MG (calcinates, tissue thickening, parenchymal deformity, derivative), US (hypoechogenic zone, calcinates, derivative) and MRI (linear - focal or segmental contrast material accumulation, derivative) images. Radiological studies compared with postoperative histological examination of the results, diagnostic sensitivity was evaluated. The data was structured and analyzed using Microsoft Excel for 2016 and SPSS 22 packages. Statistically significant indicators were assessed at p ≤ 0.05. The results: median age - 56 years old. 69 % of women were older than 50 years. Ductal in situ tumor 93 % (40 cases) was found in post-operative histological, which grade was high and moderate (40 % and 42.5 % respectively), less low-grade ductal in situ tumor (17.5 % of cases). The most common symptom of noninvasive cancer in MG was malignant type microcalcinates - 76 % (26 cases) and similar result was achieved in the US study (56 %). MRI - focal-linear contrast material accumulation - 60 %, segmented contrast material accumulation - 35 %. MG sensitivity in determining a tumor in situ was 0.79, UG - 0.70, MRI - 0.95. The study conclusions: 1. The most common non-invasive breast cancer symptoms in MG and UG images are calcinates, in MRI images - focal-linear contrast material accumulation. 2. Women, older than 50 years old, are diagnosed with non-invasive breast cancer more frequently in the prophylactic tests. 3. The most sensitive non-invasive breast cancer diagnostic method is MRI. |
