Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk

Autor: Rosenstock Julio, Perkovic Vlado, Johansen Odd Erik, Cooper Mark E., Kahn Steven E., Kollaborációs szervezet: CARMELINA Investigators, Mihály Emese, Keltai Katalin, Baló Tímea, Somogyi Anikó, Nagy Géza, Tabák Ádám, Ferencz Viktória, Domján Beatrix Annamária, Tänczer Tímea, Bajnok László Zoltán, Szujó Szabina, Nemes Orsolya, Mezősi Emese, Bódis Beáta, Márton Zsolt, Takács Róbert, Ábrahám György, Fehértemplomi Katalin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
DOI: 10.1001/jama.2018.18269
Popis: IMPORTANCE Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4) inhibitors but have included limited numbers of patients with high CV risk and chronic kidney disease.
Databáze: OpenAIRE