| Popis: |
The microscopic picture of a stomach ulcer is characterized by an atrophy of a mucous membrane in edges of a ulcer, growth of a connecting fabric and metaplasia of epitelium. 108 patients suffering from HP-associated gastric ulcer disease were randomly divided into two groups. The I group of patients was cured with standard three or four component methods of therapy included of two antibiotics (usually Klaritromycin and Amoxicillin), proton pomp inhibitors and H2 receptor antagonists. Patients of the second group were treated with the same therapy, but instead of antibiotics they received 0,1 mg rIL-2 Roncoleukin into four six points submucously using gastroscope techniques and 0,4 mg was dissolved in 400 ml 0,9% NaCl with 4 ml 10% human albumin and infused intravenously. On 3 month of monitoring 95,35% patients of the basic group completely did not have inflammatory changes GMG against 73,85% in the II, and intestinal metaplasia of epitelium was kept only at 18,6% in the I group against 36,92% cases in the II. In the basic group ulcer epithelization period was 10,79±0,46 days against 35,23±1,58 days at the patients receiving traditional therapy. |
