Proteomics and matrix-assisted laser desorption/ionization mass spectrometry imaging as a modern diagnostic tool in kidney diseases

Autor: IVANOVA MARIIA, DYADYK OLENA, SMITH ANDREW, SANTORELLI LUCIA, STELLA MARTINA, GALLI MANUEL, CHINELLO CLIZIA, MAGNI FULVIO
Jazyk: ruština
Rok vydání: 2017
Předmět:
СHRONIC KIDNEY DISEASE
PROTEOMICS
MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY IMAGING
СHRONIC KIDNEY DISEASE OUTCOME PROGNOSIS
PREDICT TREATMENT RESPONSE
ХРОНИЧЕСКАЯ БОЛЕЗНЬ ПОЧЕК
ПРОТЕОМИКА
МАСС-СПЕКТРОМЕТРИЯ С МАТРИЧНО-АКТИВИРОВАННОЙ ЛАЗЕРНОЙ ДЕСОРБЦИЕЙ/ИОНИЗАЦИЕЙ
ПРОГНОЗИРОВАНИЕ ИСХОДА ХРОНИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК
ПРОГНОЗИРОВАНИЕ ОТВЕТА НА ЛЕЧЕНИЕ
ХРОНіЧНА ХВОРОБА НИРОК
ПРОТЕОМіКА
МАС-СПЕКТРОМЕТРіЯ З МАТРИЧНО-АКТИВОВАНОЮ ЛАЗЕРНОЮ ДЕСОРБЦієЮ/іОНіЗАЦієЮ
ПРОГНОЗУВАННЯ РЕЗУЛЬТАТУ ХРОНіЧНОї ХВОРОБИ НИРОК
ПРОГНОЗУВАННЯ ВіДПОВіДі НА ЛіКУВАННЯ
Zdroj: Почки.
ISSN: 2307-1265
2307-1257
Popis: As a result of the rapid evolution of modern science, we are continually improving our knowledge of disease pathogenesis and morphology on a daily basis. Due to the era of omics sciences, such as genomics, transcriptomics, and proteomics, there is a strong desire to comprehend the molecular mechanisms of diseases and organisms. The final aims would be to perform more successful diagnosis/prognosis, identify potential therapeutic targets, and predict treatment response. Chronic kidney disease (CKD) is a worldwide health problem with a rapidly increasing incidence, with CKD itself encompassing a large subset of diseases. Recently, modern proteomic technologies, such as matrix-assisted laser desorption/ionization mass spectrometry imaging, have been employed in order to study CKD. Notwithstanding the general infancy of these methodologies, there are already an impressive number of studies and publications related to this subject.
Databáze: OpenAIRE
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