| Autor: |
Desikan, Anita Tara, Crichton, Siobhan Laura, Hoang, Uy Trong, Barratt, Benjamin Malyon, Beevers, Sean David, Kelly, Frank James, Wolfe, Charles David Alexander |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Desikan, A T, Crichton, S L, Hoang, U T, Barratt, B M, Beevers, S D, Kelly, F J & Wolfe, C D A 2016, ' The effect of exhaust and non-exhaust related components of particulate matter on long-term survival after stroke ', Stroke . |
| Popis: |
Background and Purpose: Outdoor air pollution represents a potentially modifiable risk factor for stroke. We examined the link between ambient pollution and mortality up to 5 years post-stroke, especially for pollutants associated with vehicle exhaust. Methods: Data from the South London Stroke Register, a population-based register covering an urban, multi-ethnic population was used. Hazard ratios (HR) for a one interquartile range increase in particulate matter Results: The hazard of death associated with PM2.5 up to 5 years after stroke was significantly elevated (p’s=0.006) for all strokes (HR=1.28, 95%CI 1.08-1.53) and ischaemic strokes (HR=1.32, 95%CI 1.08-1.62). Within ischaemic subtypes, PM2.5 pollution increased mortality risk for total anterior circulation infarcts (TACI) by two-fold (HR=2.01, 95%CI 1.17-3.48, p=0.012) and by 78% for lacunar infarcts (LACI) (HR=1.78, 95%CI 1.18-2.66, p=0.006). PM10 pollution was associated with 45% increased mortality risk for LACI strokes (HR=1.45, 95%CI 1.06-2.00, p=0.022). Separating PM2.5 and PM10 into exhaust and non-exhaust components did not show increased mortality. Conclusions: Exposure to certain outdoor particulate matter pollution, particularly particulate matter |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
