The Challenges of Preventing Food Allergy:lessons learned from LEAP and EAT
| Autor: | Fisher, Helen, Toit, George Du, Bahnson, Henry T., Lack, Gideon |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
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Odds Ratio Peanut allergy HE Hen's Egg IVA Instrumental Variable Analysis PETIT Prevention of Egg Allergy with Tiny Amount Intake study WHO World Health Organization Food allergy PN Peanut RR Relative Risk PP Per Protocol RCT Randomised Controlled Trial AR Absolute Risk Adj RR Adjusted Relative Risk STAR Solids Timing for Allergy Reduction Egg allergy OFC Oral Food Challenge ARR Absolute Risk Reduction HEAP Hen's Egg Allergy Prevention Prevention ASCIA Australasian Society of Clinical and Immunology and Allergy LEAP Learning Early About Peanuts food and beverages Oral tolerance induction FS Food Allergic Sensitisation [Abbreviations/Acronyms] ITT Intention to Treat CI Confidence Interval IgE Immunoglobulin E NIAID National Institute of Allergy and Infectious Diseases SPT Skin Prick Test BEAT Beating Egg Allergy STEP Starting Time of Egg Protein EAT Enquiring About Tolerance |
| Zdroj: | Fisher, H, Toit, G D, Bahnson, H T & Lack, G 2018, ' The Challenges of Preventing Food Allergy : lessons learned from LEAP and EAT ', Annals of Allergy Asthma and Immunology . https://doi.org/10.1016/j.anai.2018.06.008 |
| DOI: | 10.1016/j.anai.2018.06.008 |
| Popis: | Allergy testing and/or supervised first introduction of the specific allergenic food is advisable for infants with eczema and/or pre-existing food allergy prior to oral tolerance inductionA weekly dose of 2g of peanut or egg protein appears to be protective against peanut or egg allergyOral tolerance induction is allergen specific and has only been proven to be successful in single introduction trials of peanut and egg; multiple allergen oral tolerance induction is a significant unmet need which requires investigation using novel approaches.The addition of peanut, and other common food allergens (egg, fish, sesame, milk) to the infant diet has no adverse nutritional or growth effects and does not increase rates of food allergy. Breastfeeding rates are not adversely affected by these interventions in a clinical trial setting.In the Western world, non-white children have the highest risk of food allergy but their families are the least likely to take up oral tolerance induction programmes; strategies to promote oral tolerance induction in non-white families are required |
| Databáze: | OpenAIRE |
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