HIV Skews a Balanced Mtb-Specific Th17 Response in Latent Tuberculosis Subjects to a Pro-inflammatory Profile Independent of Viral Load:HIV alters the nature of the Mtb-specific Th17 response
| Autor: | Rakshit, Srabanti, Hingankar, Nitin, Alampalli, Shuba Varshini, Adiga, Vasista, Sundararaj, Bharath K., Sahoo, Pravat Nalini, Finak, Greg, Uday Kumar J, Anto Jesuraj, Dhar, Chirag, D'Souza, George, Virkar, Rashmi Govind, Ghate, Manisha, Thakar, Madhuri R., Paranjape, Ramesh S., De Rosa, Stephen C., Ottenhoff, Tom H.M., Vyakarnam, Annapurna |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Rakshit, S, Hingankar, N, Alampalli, S V, Adiga, V, Sundararaj, B K, Sahoo, P N, Finak, G, Uday Kumar J, A J, Dhar, C, D'Souza, G, Virkar, R G, Ghate, M, Thakar, M R, Paranjape, R S, De Rosa, S C, Ottenhoff, T H M & Vyakarnam, A 2020, ' HIV Skews a Balanced Mtb-Specific Th17 Response in Latent Tuberculosis Subjects to a Pro-inflammatory Profile Independent of Viral Load : HIV alters the nature of the Mtb-specific Th17 response ', Cell Reports, vol. 33, no. 9, 108451 . https://doi.org/10.1016/j.celrep.2020.108451 |
| DOI: | 10.1016/j.celrep.2020.108451 |
| Popis: | This study provides insight on how HIV may drive tuberculosis (TB). Rakshit et al. demonstrate that HIV infection of latent TB subjects profoundly alters specific immune subsets implicated in anti-TB immunity, which is independent of cellular viral burden or secretion of antiviral chemokines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|