| Autor: |
Kolbitsch, Christoph, Neji, Radhouene, Fenchel, Matthias, Mallia, Andrew, Marsden, Paul, Schaeffter, Tobias |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Kolbitsch, C, Neji, R, Fenchel, M, Mallia, A, Marsden, P & Schaeffter, T 2018, ' Fully integrated 3D high-resolution multicontrast abdominal PET-MR with high scan efficiency ', Magnetic Resonance in Medicine, vol. 79, no. 2, pp. 900-911 . https://doi.org/10.1002/mrm.26757 |
| DOI: |
10.1002/mrm.26757 |
| Popis: |
Purpose: To provide 3D multicontrast anatomical MR with high isotropic resolution and metabolic positron emission tomography (PET) images using a respiratory motion-compensated simultaneous PET-MR examination with high scan efficiency. Theory and Methods: Standard abdominal PET-MR examinations combine MR data obtained during multiple breath-holds with free-breathing PET acquisitions, limiting the achievable image resolution and potentially causing misalignment errors between breath-hold and free-breathing data. Here, a 3D free-breathing PET-MR acquisition is presented, yielding T1 and T2-weighted MR images with an isotropic resolution of 1.5mm3. In addition, nonrigid respiratory motion information and respiratory-resolved attenuation-correction maps are obtained without an increase in scan time. Motion information is used in motion-compensated image reconstructions to improve MR and PET image quality while shortening scan times. Results: The proposed approach was evaluated in 11 oncology patients and provided respiratory motion information with an accuracy of 1.3±0.1mm. Sharpness of anatomical features was increased by 19±13% compared with the uncorrected MR images in a 54±26% shorter scan time than a gated MR acquisition. The MR-based motion information improved uptake values (75±94%) and resolution (16±27%) of simultaneously acquired PET images. Conclusions: The proposed method provides motion-compensated 3D high-quality MR and PET images in a comprehensive and highly efficient examination. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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