Tarmfloraens indflydelse på adfærd i den subkroniske PCP inducerede dyremodel for schizofreni

Autor:	Jørgensen, Bettina Merete Pyndt, Redrobe, Paul, Brønnum Pedersen, Tina, Selfjord, Ellika Marie, Nielsen, Dennis Sandris, Plath, Niels, Hansen, Axel Kornerup, Sørensen, Dorte Bratbo
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	stomatognathic diseases fluids and secretions behavior digestive oral and skin physiology Schizophrenia Gut microbiota Animal Model digestive system Faculty of Social Sciences
Zdroj:	Jørgensen, B M P, Redrobe, P, Brønnum Pedersen, T, Selfjord, E M, Nielsen, D S, Plath, N, Hansen, A K & Sørensen, D B 2013, ' The gut microbiota influence behavior in the subchronic PCP induced animal model of schizophrenia ', Neurodag 2013, Copenhagen, Denmark, 25/10/2013-25/10/2013 .
Popis:	The gut microbiota has major impact on the individual. Here we show that the gut microbiota influence behavior in the subchronic PCP induced animal model of schizophrenia. The gut microbiota were changed in the group treated subchronic with PCP, and restoration coincided with normalisation of memory performance in lister hooded rats. Furthermore the individual gut microbiota correlated to the individual behavior abserved in the tests conducted. In conclusion results show an influence of the gut microbiota on behavior in this model, and therefore it might be relavant to include the information from the gut in analyses of studies using this model in the future.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______2751::f4603f06e75dd4e14b571c3293c209fc https://curis.ku.dk/portal/da/publications/the-gut-microbiota-influence-behavior-in-the-subchronic-pcp-induced-animal-model-of-schizophrenia(d62a5101-179f-422a-ad1c-a37874049071).html Zobrazit plný text záznamu