| Autor: |
Bogh, Adrian F., Jensen, Simon B K, Juhl, Christian R, Janus, Charlotte, Sandsdal, Rasmus M, Lundgren, Julie R, Noer, Mikkel H., Vu, Nhu Q., Fiorenza, Matteo, Stallknecht, Bente M, Holst, Jens J., Madsbad, Sten, Torekov, Signe S. |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Zdroj: |
Bogh, A F, Jensen, S B K, Juhl, C R, Janus, C, Sandsdal, R M, Lundgren, J R, Noer, M H, Vu, N Q, Fiorenza, M, Stallknecht, B M, Holst, J J, Madsbad, S & Torekov, S S 2023, ' Insufficient sleep predicts poor weight loss maintenance after one year ', Sleep, vol. 46, no. 5, zsac295 . https://doi.org/10.1093/sleep/zsac295 |
| Popis: |
STUDY OBJECTIVES: Insufficient sleep may attenuate weight loss, but the role of sleep in weight loss maintenance is unknown. Since weight regain after weight loss remains a major obstacle in obesity treatment, we investigated whether insufficient sleep predicts weight regain during weight loss maintenance.METHODS: In a randomized, controlled, two-by-two factorial study, 195 adults with obesity completed an eight-week low-calorie diet and were randomly assigned to one-year weight loss maintenance with or without exercise and liraglutide 3.0mg/day or placebo. Sleep duration and quality were measured before and after the low-calorie diet and during weight maintenance using wrist-worn accelerometers (GENEActiv) and Pittsburgh Sleep Quality Index. To test associations between insufficient sleep and weight regain, participants were stratified at randomization into subgroups according to sleep duration (5).RESULTS: After a diet-induced 13.1 kg weight loss, participants with short sleep duration at randomization regained 5.3 kg body weight (P=.0008) and had less reduction in body fat percentage compared with participants with normal sleep duration (P=.007) during the one-year weight maintenance phase. Participants with poor sleep quality before the weight loss regained 3.5 kg body weight compared with good quality sleepers (P=.010). During the weight maintenance phase, participants undergoing liraglutide treatment displayed increased sleep duration compared with placebo after 26 weeks (5 vs. -15 min/night) but not after one year. Participants undergoing exercise treatment preserved the sleep quality improvements attained from the initial weight loss.CONCLUSIONS: Short sleep duration or poor sleep quality was associated with weight regain after weight loss in adults with obesity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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