Ni-Catalyzed Carboxylation of Aziridines en Route to β‑Amino Acids
| Autor: | Davis, Jacob, Janssen-Müller, Daniel, Zimi, Dmitry P., Yanagi, Tomoyuki, Elfert, Jonas, Martin, Ruben |
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| Rok vydání: | 2021 |
| Popis: | A Ni-catalyzed reductive carboxylation ofN-substituted aziridines with CO2at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access β-amino acids, important building blocks with considerable potential as peptidomimetics. |
| Databáze: | OpenAIRE |
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