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Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych Dariya V., Badiuk Nataliya S., Żukow Xawery. “Myroslava” and “Khrystyna” drinking mineral waters modulate the state of neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa. Journal of Education, Health and Sport. 2022;12(3):11-23. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.03.001 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.03.001 https://zenodo.org/record/6327200 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.02.2022. Revised: 28.02.2022. Accepted: 04.03.2022. “MYROSLAVA” AND “KHRYSTYNA” DRINKING MINERAL WATERS MODULATE THE STATE OF NEUROENDOCRINE-IMMUNE COMPLEX AND METABOLISM IN PATIENTS OF TRUSKAVETS’ SPA Anatoliy I. Gozhenko1, Myroslava V. Hrytsak1,2, Dariya V. Popovych3, Nataliya S. Badiuk1,4, Xawery Żukow5 1SE Ukrainian Research Institute of Medicine of Transport, Odesa, Ukraine badiuk_ns@ukr.net 2Scientific group of Balneology of Hotel&Spa Complex "Karpaty", Truskavets’, Ukraine hrytsak.myroslava@gmail.com ira_barschyk@ukr.net 3IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine darakoz@yahoo.com 4International Medical University, Odesa, Ukraine 5Medical University of Bialystok, Bialystok, Poland xaweryzukow@gmail.com Background. Earlier in an experiment on rats we showed that newly created sulfate-chloride sodium-magnesium drinking mineral waters "Myroslava" and "Khrystyna" of Truskavets’ spa has a significant modulating effects on the parameters of metabolism and the autonomic nervous, endocrine and immune systems. Adhering to the principle "Ex experimento ad clinic", we continued research in this direction with the participation of patients of the resort. We showed that these mineral waters have favorable effects on metabolic, HRVs, EEGs, endocrine and immune parameters. This article presents an integrated assessment of previously identified effects. Materials and Methods. The object of clinical-physiological observation were 34 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa. The examination was performed twice, before and after a 7-10-day course of balneotherapy. All patients received bioactive water Naftussya, however, 11 men additionally drank water "Khrystyna", and the other 11 men water "Myroslava". The subject of the study were the parameters of the neuroendocrine-immune complex and metabolism. Results. The complex balneotherapy by interval use of sulfate-chloride sodium-magnesium mineral waters with Naftusya water causes significant changes in the constellation of EEGs, HRVs, endocrine, metabolic and immune parameters, which are different from the effects of Naftusya water monotherapy. Own effects of mineral waters are estimated by modeling. In general, the effects are physiologically favorable and have a normalizing nature. Conclusion. The newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have favorable neuroendocrine, metabolic and immune effects on patients with chronic cholecystitis and pyelonephritis. Keywords: sulfate-chloride sodium-magnesium drinking mineral waters, Truskavets’ spa, EEG, HRV, hormones, metabolism, immunity. |
