| Popis: |
Exaptation is process that is characterised by evolution of characteristics, its evolution for other usages, and later co-opted for their current role. In pharmaceutical industry, innovations have high potential in terms of competitive advantage and profit, but are also connected with high risks associated with costs, time and uncertainty. In order to minimize risks, companies are frequently choosing strategy of exaptation in terms of redeveloping compound for use in a different disease. Intention of this research is to provide analysis and quantification (measurement) of drugs that have been exaptated through process of drug reposition. Results indicates that on level of 6098 clinical studies Phase I we have observed total of 659 drugs/substances (~11%) that have been used in more than one clinical research for the same or different indication showing level of exaptation use in clinical research. Keywords: exaptation, drug reposition, pharmaceutical industry, innovation, pharmacoeconomics, research and development |
