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PopovychIgor L., Gozhenko Anatoliy I., Hrytsak Myroslava V., PopovychDariya V., Badiuk Nataliya S., Zukow Walery. Peculiarities of modulating effects of “Myroslava” and “Khrystyna” mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa.Journal of Education, Health and Sport. 2022;12(3):53-66.eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.03.005 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.03.005 https://zenodo.org/record/6350608 The journal has had 40points in Ministry of Educationand Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok40punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r.Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu);Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.02.2022. Revised: 28.02.2022. Accepted: 13.03.2022. Peculiarities of modulating effects of “Myroslava” and “Khrystyna” mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa Igor L. Popovych1,2, Anatoliy I. Gozhenko1,4, Myroslava V. Hrytsak1,2, Dariya V. Popovych3, Nataliya S. Badiuk1,4, Walery Zukow5 1SE Ukrainian Research Institute of Medicine of Transport, Odesa badiuk_ns@ukr.net 2Scientific group of Balneology of Hotel&Spa Complex "Karpaty", Truskavets’, Ukraine hrytsak.myroslava@gmail.comira_barschyk@ukr.net 3IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine darakoz@yahoo.com 4International Medical University, Odesa, Ukraine 5Nicolaus Copernicus University, Torun, Poland w.zukow@wp.pl Abstract Background.Earlier we found effects on the neuroendocrine-immune complex and metabolism, which are common to the mineral waters "Myroslava" and "Khrystyna", instead different from the effects of Naftussya water.The purpose of this article is to find the specific effects of these waters.Materials and Methods.The object of clinical-physiological observation were 22 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa.The examination was performed twice, before and after a 7-10-day course of balneotherapy.Half of the patients received bioactive water Naftussyaand sulfate-chloride sodium-magnesium mineral water "Myroslava" (M 5 g/L), and the other half - Naftussyaand"Khrystyna" (M 10 g/L).The subject of the study were the parameters of the neuroendocrine-immune complex, microbiota, cholekineticsand metabolism. Results. Screening revealed specific changes in 37 parameters grouped into 5 patterns. The first pattern combines 11 parameters that decrease under the influence of "Myroslava" water (Myr), while increase under the influence of "Khrystyna" water (Khr). For the other 7 parameters of the second pattern, Myr acts similarly, while Khr is ineffective.Both mineral waters have a stimulating effect on 8 parameters, while Myr is inferior to Khr.Myr has a upregulating effect on 9 parameters of the fourth pattern, while Khr has a downregulating effect.Finally, sodium excretion and leukocyturia are reduced under the influence of both waters, but to a greater extent under the influence of Khr.Conclusion. The newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have both common and specific favorablemodulatingneuroendocrine, metabolic and immune effects on patients withchronic cholecystitis and pyelonephritis. Keywords:sulfate-chloride sodium-magnesium drinking mineral waters, Truskavets’ spa, EEG, HRV, hormones, metabolism, immunity. |
