| Autor: |
Alica C. Keuper, Kevin Fengler, Florian Ostler, Tobias Danelzik, Dariusz G. Piekarski, Olga García Mancheño |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Popis: |
Anew approach towards highly enantioselective halogen-bonding catalysis hasbeen developed. In order to circumvent the intrinsic issues of the halogen-bond(XB)natureand consequent unresolved limitations in asymmetric catalysis,fine-tuned halogen--halogen interactions between the substrate and XB-donor were designed to pre-organize the substrate in the catalyst’s cavity and boost enantiocontrol. Remarkable enantioselectivities of up to 95:5 e.r. (90% ee) have been achieved in a model dearomatization reaction of halogen-substituted (iso)quinolines with tetrakis-iodotriazole multidentate anion-binding catalysts |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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