Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit

Autor:	Prince, Luke, Bacon, Travis J, Tigaret, Cezar, Mellor, Jack
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	computational modeling Serotonin hippocampal nervous system musculoskeletal neural and ocular physiology noradrenaline CA3 dentate gyrus dopamine mossy fibers acetylcholine
Zdroj:	Prince, L, Bacon, T J, Tigaret, C & Mellor, J 2016, ' Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit ', Frontiers in Synaptic Neuroscience, vol. 8, 32 . https://doi.org/10.3389/fnsyn.2016.00032
DOI:	10.3389/fnsyn.2016.00032
Popis:	The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories. The creation of these CA3 ensembles depends on neuromodulatory input and synaptic plasticity within this microcircuit. Here we review the mechanisms by which the neuromodulators aceylcholine, noradrenaline, dopamine, and serotonin reconfigure this microcircuit and thereby infer the net effect of these modulators on the processes of episodic memory encoding and retrieval.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______2642::12e99e958a43271b90c5592c88458171 https://research-information.bris.ac.uk/ws/files/90223805/fnsyn_08_00032.pdf Zobrazit plný text záznamu