Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review
| Autor: | Rueda-Robles, Ascensión, Rubio-Tomás, Teresa, Plaza-Diaz, Julio, Álvarez-Mercado, Ana I. |
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| Přispěvatelé: | [Rueda-Robles,A, Álvarez-Mercado,AI] Center of Biomedical Research, Institute of Nutrition and Food Technology 'José Mataix', University of Granada, Armilla, Granada, Spain. [Rubio-Tomás,T] Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. [Rubio-Tomás,T] School of Medicine, University of Crete, Heraklion, Crete, Greece. [Plaza-Diaz,J] Children’s Hospital Eastern Ontario Research Institute, Ottawa, Canada. [Plaza-Diaz,J, Álvarez-Mercado,AI] Department of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Granada, Spain. [Plaza-Diaz,J, Álvarez-Mercado,AI] Instituto de Investigación Biosanitaria ibs.GRANADA, Complejo Hospitalario Universitario de Granada, Granada, Spain. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Phenomena and Processes::Microbiological Phenomena::Virulence [Medical Subject Headings]
Microbioma gastrointestinal Disbiosis Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings] Diseases::Digestive System Diseases::Gastrointestinal Diseases::Stomach Diseases [Medical Subject Headings] Therapeutic approaches Conductas terapéuticas Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms Glandular and Epithelial::Carcinoma::Adenocarcinoma [Medical Subject Headings] Gastrointestinal microbiota Peptic ulcer Diseases::Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Gastritis [Medical Subject Headings] Helicobacter pylori Úlcera péptica Organisms::Bacteria::Proteobacteria::Epsilonproteobacteria::Helicobacter::Helicobacter pylori [Medical Subject Headings] Phenomena and Processes::Immune System Phenomena::Immunity [Medical Subject Headings] Diseases::Neoplasms::Neoplasms by Histologic Type::Lymphoma::Lymphoma Non-Hodgkin::Lymphoma B-Cell::Lymphoma B-Cell Marginal Zone [Medical Subject Headings] Diet Phenomena and Processes::Microbiological Phenomena::Microbiota [Medical Subject Headings] Gastritis Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Micronutrients [Medical Subject Headings] Dysbiosis Dieta Modelos teóricos Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Dysbiosis [Medical Subject Headings] Diseases::Digestive System Diseases::Gastrointestinal Diseases::Peptic Ulcer [Medical Subject Headings] Experimental models |
| Popis: | Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. This bacterium is responsible for long-term complications of gastric disease. The conjunction of host genetics, immune response, bacterial virulence expression, diet, micronutrient availability, and microbiome structure influence the disease outcomes related to chronic H. pylori infection. In this regard, the consumption of unhealthy and unbalanced diets can induce microbial dysbiosis, which infection with H. pylori may contribute to. However, to date, clinical trials have reported controversial results and current knowledge in this field is inconclusive. Here, we review preclinical studies concerning the changes produced in the microbiota that may be related to H. pylori infection, as well as the involvement of diet. We summarize and discuss the last approaches based on the modulation of the microbiota to improve the negative impact of H. pylori infection and their potential translation from bench to bedside. Yes |
| Databáze: | OpenAIRE |
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