Basic Quality Controls Used in Skin Tissue Engineering
Autor: | Linares-Gonzalez, Laura, Rodenas-Herranz, Teresa, Campos, Fernando, Ruiz-Villaverde, Ricardo, Carriel, Víctor |
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Přispěvatelé: | [Linares-Gonzalez,L, Rodenas-Herranz,T, Ruiz-Villaverde,R] Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, Spain. [Linares-Gonzalez,L, Campos,F, Ruiz-Villaverde,R, Carriel,V] Ibs. GRANADA, Instituto Biosanitario de Granada, Granada, Spain. [Linares-Gonzalez,L, Carriel,V] Department of Histology, University of Granada, Granada, Spain., Supported by PE-0395-2019 from Consejería de Salud y Familias, Junta de Andalucía, Spain. |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Chemicals and Drugs::Biomedical and Dental Materials::Biocompatible Materials [Medical Subject Headings]
Biomechanical evaluation Quality control Analytical Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Surgical Equipment::Artificial Organs::Skin Artificial [Medical Subject Headings] Fenómenos bioquímicos Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Weights and Measures::Reference Standards [Medical Subject Headings] Phenomena and Processes::Biological Phenomena::Biological Processes::Regeneration::Wound Healing [Medical Subject Headings] Control de calidad Reacciones bioquímicas Enfermedades de la piel y tejido conjuntivo Técnicas histológicas Histological techniques Biochemical methods Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering [Medical Subject Headings] Skin tissue engineering |
Popis: | Reconstruction of skin defects is often a challenging effort due to the currently limited reconstructive options. In this sense, tissue engineering has emerged as a possible alternative to replace or repair diseased or damaged tissues from the patient's own cells. A substantial number of tissue-engineered skin substitutes (TESSs) have been conceived and evaluated in vitro and in vivo showing promising results in the preclinical stage. However, only a few constructs have been used in the clinic. The lack of standardization in evaluation methods employed may in part be responsible for this discrepancy. This review covers the most well-known and up-to-date methods for evaluating the optimization of new TESSs and orientative guidelines for the evaluation of TESSs are proposed. Yes |
Databáze: | OpenAIRE |
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