| Přispěvatelé: |
[Pineda,R, Torres,E, Tena-Sempere,M] Instituto Maimónides de Investigación Biomédica de Cordoba (IMIBIC), Cordoba, Spain. [Pineda,R, Tena-Sempere,M] Department of Cell Biology, Physiology and Immunology, University of Cordoba, Cordoba, Spain. [Pineda,R, Tena-Sempere,M] Hospital Universitario Reina Sofia, Cordoba, Spain. [Pineda,R, Tena-Sempere,M] CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Cordoba, Spain. [Tena-Sempere,M] Institute of Biomedicine, University of Turku, Turku, Finland., The work from the authors’ laboratory reviewed herein was supported by grant BFU2017-83934-P and PID2020-118660GB-I00 (Agencia Estatal de Investigación, Spain, co-funded with EU funds from FEDER Program), Projects P18-RT-4093 (to M.T.-S.) and grant P18-RTJ-4163 (to R.P., (Junta de Andalucía, Spain), and Project 1254821 (University of Cordoba-FEDER). CIBER is an initiative of Instituto de Salud Carlos III (Ministerio de Sanidad, Spain). |
| Popis: |
Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., nutritional) conditions. As such, this function is sensitive to and closely connected with other relevant bodily systems, including reproduction and gonadal function. The aim of this mini-review article is to summarize the most salient experimental data supporting a role of the amygdala as a key brain region for emotional learning and behavior, including reward processing, in the physiological control of feeding and energy balance. In particular, a major focus will be placed on the putative interplay between reproductive signals and amygdala pathways, as it pertains to the control of metabolism, as complementary, extrahypothalamic circuit for the integral control of energy balance and gonadal function. Yes |
