Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia

Autor: Martinez-Lopez, Antonio, Montero-Vilchez, Trinidad, Sierra-Sánchez, Álvaro, Molina-Leyva, Alejandro, Arias-Santiago, Salvador
Přispěvatelé: [Martinez-Lopez,A, Montero-Vilchez,T, Molina-Leyva,A, Arias-Santiago,S] Dermatology Unit, Virgen de las Nieves University Hospital, Granada, Spain. [Martinez-Lopez,A, Arias-Santiago,S] TECe19-Clinical and Translational Dermatology Investigation Group, Ibs.Granada, Granada, Spain. [Sierra-Sánchez,A, Arias-Santiago,S] Cell Production and Tissue Engineering Unit, Virgen de las Nieves University Hospital, Andalusian Network of Design and Translation of Advanced Therapies, Granada, Spain. [Sierra-Sánchez,A, Arias-Santiago,S] Biosanitary Institute of Granada (ibs.GRANADA), Granada, Spain. [Arias-Santiago,S] Dermatology Department, Granada School of Medicine, Granada University, Granada, Spain., Financial support from Instituto de Salud Carlos III through the projects PI-17/02083 (co-funded by European Regional Development Fund 'A way to make Europe') and Ministry of Health of the Andalusian Regional Government (SAS PI-0458-2016 and AML PIGE-0249-2019).
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Disciplines and Occupations::Health Occupations::Medicine::Dermatology [Medical Subject Headings]
Alopecia areata
Advanced medical therapies
Células madre mesenquimatosas
Alopecia
Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia [Medical Subject Headings]
Anatomy::Tissues::Epithelium::Epidermis::Hair Follicle [Medical Subject Headings]
Terapia genética
Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia::Alopecia Areata [Medical Subject Headings]
Anatomy::Integumentary System::Skin [Medical Subject Headings]
Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]
Gene therapy
Organisms::Eukaryota::Animals [Medical Subject Headings]
Mesenchymal stem cells
Tissue engineering
Ingeniería de tejidos
skin and connective tissue diseases
Androgenic alopecia
Analytical
Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering [Medical Subject Headings]
Popis: Alopecia is a challenging condition for both physicians and patients. Several topical, intralesional, oral, and surgical treatments have been developed in recent decades, but some of those therapies only provide partial improvement. Advanced medical therapies are medical products based on genes, cells, and/or tissue engineering products that have properties in regenerating, repairing, or replacing human tissue. In recent years, numerous applications have been described for advanced medical therapies. With this background, those therapies may have a role in the treatment of various types of alopecia such as alopecia areata and androgenic alopecia. The aim of this review is to provide dermatologists an overview of the different advanced medical therapies that have been applied in the treatment of alopecia, by reviewing clinical and basic research studies as well as ongoing clinical trials. Yes
Databáze: OpenAIRE