The Effect of Therapeutic Hypothermia after Cardiac Arrest on the Neurological Outcome and Survival-A Systematic Review of RCTs Published between 2016 and 2020
Autor: | Colls Garrido, Christian, Riquelme Gallego, Blanca, Sánchez García, Juan Carlos, Cortés Martín, Jonathan, Montiel Troya, María, Rodríguez Blanque, Raquel |
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Přispěvatelé: | [Colls Garrido,C] Intensive Care Unit, Hospital Universitario Clínico San Cecilio, Granada, Spain. [Riquelme Gallego,B, Sánchez García,JC, Cortés Martín,J] School of Nursing, Faculty of Health Sciences, University of Granada, Granada, Spain. [Riquelme Gallego,B] Instituto de Investigación Biosanitaria, ibs.GRANADA, Granada, Spain. [Sánchez García,JC, Cortés Martín,J, Montiel Troya,M, Rodríguez Blanque,R] Research Group CTS1068, Andalusia Research Plan, Junta de Andalucía, Granada, Spain. [Montiel Troya,M] School of Nursing Ceuta Campus, Faculty of Health Sciences, University of Granada, Ceuta, Spain. [Rodríguez Blanque,R] Distrito Sanitario Granada-Metropolitano, Granada, Spain. |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Survival rate
Information Science::Information Science::Data Collection::Vital Statistics::Mortality::Survival Rate [Medical Subject Headings] Diseases::Cardiovascular Diseases::Heart Diseases::Heart Arrest [Medical Subject Headings] Neuroprotección Revisión sistemática Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Cryotherapy::Hypothermia Induced [Medical Subject Headings] Cardiac arrest Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Hyperthermia Induced [Medical Subject Headings] Health Care::Health Care Facilities Manpower and Services::Health Services::Patient Care::Critical Care [Medical Subject Headings] Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Critical care Tasa de supervivencia Persons::Persons::Age Groups::Child [Medical Subject Headings] Hipotermia inducida Paro cardíaco Metaanálisis Persons::Persons::Age Groups::Adult [Medical Subject Headings] Cuidados críticos Induced hypothermia |
Popis: | Therapeutic hypothermia is a treatment used for patients who have suffered cardiores piratory arrest and remain conscious after the recovery of spontaneous circulation. However, its effectiveness is controversial. The objective of this systematic review is to summarize the scientific evidence available about the effect of therapeutic hypothermia on neurological status and survival in this type of patients. Methodology: A primary search in CINAHL, CUIDEN, Pubmed, Web of Science, and Scopus databases was carried out. Randomized clinical trials (RCT) published from 2016 to 2020 were selected. Results: 17 studies were selected for inclusion and most relevant data were extracted. Methodological quality was assessed by the RoB tool. Conclusions: Although therapeutic hypothermia is a safe technique with few adverse and manageable effects, it has not shown to improve survival rate and neurological status of adult nor pediatric patients. It is possible that its positive effect on neuroprotection could be achieved only by preventing hyperthermia although further investigation is needed. Yes |
Databáze: | OpenAIRE |
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