Mechanical thrombectomy in acute stroke patients during covid-19; comparison of pre-pandemic and pandemic data

Autor: Çapar, Ahmet Ergin, Sercan Bıtrak, Gözde, Baş, Demet Funda, Sarıoğlu, Orkun, Arslan, Kebire Eylül, Şener, Ufuk, Köse, Şükran, Atasoy, Görkem
Jazyk: angličtina
Rok vydání: 2023
Popis: Aim: To evaluate the reflection of the pandemic, on the mechanical thrombectomy (MT) management of acutestrokeMethod: We retrospectively evaluated 100 acute ischemic stroke patients between March 1, 2019- Februray 29,2020, and between March 1, 2020 - March 1, 2021, who underwent MT at our institute. Patients were divided intotwo groups as those who underwent MT before the Covid 19 pandemic (group 1) and those who underwent MTduring the period of Covid 19 pandemic (group 2). All the diagnosis of stroke patients was confirmed by MRI and CT.Demographics, clinical and laboratory data were recorded. National Institutes of Health Stroke Scale (NIHSS) scoreon pre-hospitalization and at discharge, ASPECT score, occluded vessel location, use of preprocedural lyticmedication, modified Rankin scores (mRS), procedure times (onset to groin puncture, door to needle, groin punctureto recanalization), device pass counts until successful recanalization or last angiogram if recanalization failed,Thrombolysis in Cerebral İnfarction (TICI) scales, early neurological improvements, post-procedure hemorrhage,decompression surgery, type of anesthesia during procedure and periprocedural complications were analyzedbetween groups. TOAST classification was used for stroke etiology.MT findings; symptom onset to groin puncture and recanalization times, first pass effect defined with single devicepass with TICI 2b/3 recanalization and final recanalization, admission and NIHHS scores and 3rd month mRS scores,postprocedural hemorrage rates were compared between groups.The SPSS version 26.0 was used for statistical analysis. The distribution of variables was assessed by theKolmogorov- Smirnov test. Categorical variable was evaluated using Chi-square test or Fisher’s exact test. Mann-Whitney U test or independent t-test was used for comparing continuous variables.Result: A total of 100 patients, 50 before and 50 after the pandemic, were included in the study. No statisticallysignificant difference was observed between the groups in terms of demographic data and risk factors. The timefrom symptom onset to groin puncture wassignificantly longer during the pandemic period than before (p=0.001). No significant difference was observed in thetime from groin puncture to recanalization (p=0.251), recanalization rates (p=0.806) and the number of passes(p=0.889). There was no difference between the pre-pandemic and post-pandemic groups in terms of the frequencyof intracranial hemorrhage (p=0.501), complication (p=0.153) and decompression (p=0.538) after MT. The mRSscores at 3 months were similar (p=0.316).Conclusion: As a result, the time from symptom to procedure is prolonged in acute ischemic stroke patients whounderwent MT in our center during the pandemic period.İn the respect of procedural findings and outcomes of MTbefore and during pandemic, there had been no significant change at our center.
Databáze: OpenAIRE