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Background: The study aims to investigate and evaluate the factors and treatment options of global health problem of obesity which poses a serious risk for a healthy lifeMaterials and Methods: In the search for scientific literature related to this review the US National Library of Medicine (PubMed) used Medline and Sport Discus data and the terms “obesity genetics”, “obesity”, “physical activity” and ‘’ exercise ‘’ were used. The relevant literature has also taken its source from the research of relevant articles from reference lists derived from data studies.Results: Obesity is a genetic and environmental interaction disease that can cause serious and chronic problems for a healthy life. Due to the excessive amount of adipose tissue in the body, its development is a metabolic health problem that causes many health problems and requires medical treatment.Conclusion: In the light of all these facts, it can be observed that the most important risk factors of obesity, genetic predisposition, decrease in physical activity, nutritional habits, age, gender, education level stand out. Adult and child obesity is spreading rapidly all over the world, but especially in developing countries.Keywords: Obesity; Physical activity and exercise; Weight control; Obesity genetics |